Okay, just tested it with my laptop on Win 11 Pro (again with Brave): Yubikey 5 again successfull - storing the passkey in Windows Hello doesn’t even offer me “with encryption” and shows for the created passkey “encryption not supported”.
So - at least with my devices - whether it is Win 11 Home or Pro, it doesn’t work with Windows Hello and is no problem with my YubiKeys 5. (again, all tested with Brave)